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TOXINS
Toxins
are poisonous substances produced as by-products of microorganisms (the
pathogens), plants or animals. Some toxins can be chemically synthesized
and some can be artificially produced with bioengineering techniques.
Toxins exert their lethal or incapacitating effects by interfering with
certain cell and tissue functions. Basically, there are toxins that
disrupt nerve impulses (neurotoxins) and toxins that destroy cell by
disrupting cell respiration and metabolism (cytotoxins). There is a
vast range of signs and symptoms with both toxin types. These sign and
symptoms can be confused with both chemical and pathogen signs and symptoms.
The neurotoxins tend to be quick acting and produce nerve agent-like
symptoms in seconds to hours. Symptoms of neurotoxin poisoning range
from mental confusion, loss of balance, and vision problems, to a limp
paralysis or convulsive-type seizures leading to coma and death.
Cytotoxins tend to be slower acting and produce chocking, blistering
or even radiation-like symptoms in hours to days. Signs range from skin
lesions such as ulcerations or blisters to vomiting, diarrhea, coughing,
and chocking (the latter thee signs may be accompanied by bloody discharges)
to marked weakness, coma and death.
Toxins
are thousands of times more toxic than nerve agents. This enables toxins
to exert their effects, even though diluted by extensive downwind or
downstream travel. Many toxins are resistant to the denaturing effects
of high temperatures; many potential warfare toxins are resistant to
hydrolysis (a chemical reaction in which water reacts with a compound
to produce other compounds; involves the splitting of a bond and the
addition of the hydrogen cation and the hydroxide anion from the water),
and many are resistant to the breakdown or denaturing effects of ultraviolet
radiation. Some toxins can last from days to weeks. Some toxins, in
particular cytotoxins, can cause delayed effects. Unlike microorganisms,
which are living agents, toxins's delay is not caused by a growth in
number phase. The delay is caused from cell exposure to time until the
function of the body cell is disrupted, and, besides, many toxins have
a cumulative effect. Repeated exposure to small amounts (less than incapacitating
or lethal effective dose) can add up to an incapacitating or lethal
effective dose.
Toxins can cover larger areas than those covered by chemical aerosols.
Compared to the pathogens they are extremely toxic and lightweight,
particularly if employed in an aerosol. However, being chemical rather
than living, toxins are not infectious, contagious, nor capable of self
reproduction.
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